4 Reasons to Know the Neutrophil-to-Lymphocyte Ratio (NLR)

Dec 22, 2023

4 Reasons to Know the NLR

🩸 An increased NLR positively correlates with higher mortality rates and numerous health conditions such as cardiovascular disease, diabetes, hypertension, pancreatitis, sepsis, bipolar disorder, major depressive disorder, and many others.⁠

🩸 An elevated level is also associated with worse outcomes for several cancers including breast, ovarian, gastroesophageal, pancreas, colon, colorectal, hepatocellular, biliary tract, kidney, and urothelium.⁠

🩸 LabSmarts automatically calculates NLR and plots that value on a color-coded reference range bar graph with an optimal range between 1.5 to 2, supported by the studies found below and in the NLR section of our bibliography.⁠

🩸 LabSmarts also provides possible root causes, conditions, lifestyle, and environmental factors associated with increased and decreased NLR.

🩸 Click the link in our bio for labsmarts.com to sign up for your FREE LabSmarts account and try it!⁠

(1) Lee JS, Kim NY, Na SH, Youn YH, Shin CS. Reference values of neutrophil-lymphocyte ratio, lymphocyte-monocyte ratio, platelet-lymphocyte ratio, and mean platelet volume in healthy adults in South Korea. Medicine (Baltimore). 2018;97(26).⁠

(2) Ayhan MG, Cicek IE, Inanli I, Caliskan AM, Kirci Ercan S, Eren I. Neutrophil/lymphocyte and platelet/lymphocyte ratios in all mood states of bipolar disorder. Psychiatry and Clinical Psychopharmacology. 2017;27(3):278-282.⁠

(3) Halazun HJ, Mergeche JL, Mallon KA, Connolly ES, Heyer EJ. Neutrophil-lymphocyte ratio as a predictor of cognitive dysfunction in carotid endarterectomy patients. J Vasc Surg. 2014;59(3):768-773.⁠

(4) Lee SF, Luque-Fernandez MA. Prognostic value of lymphocyte-to-monocyte ratio and neutrophil-to-lymphocyte ratio in follicular lymphoma: a retrospective cohort study. BMJ Open. 2017;7(11):e017904.⁠

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